Research Associate, Entry Level (Molecular Cloning, In Vivo)

Our Mission

Engage Bio is a preclinical-stage biotechnology company pioneering the next generation of genetic medicines. Our Tethosome platform combines the potency and safety of mRNA with the durability of DNA, delivering long-lasting, non-viral gene expression. This enables the body (e.g., liver or lung) to produce therapeutic biologics for extended periods, potentially for years from a single dose. We're developing treatments for a broad spectrum of diseases, from ultra-rare genetic disorders to common conditions that affect millions.

Our Work

Fast-paced, collaborative, and mission-driven, our work is rooted in a simple but ambitious goal: the elimination of human disease. If you’re looking for a place where your work can have a meaningful impact early in your career, we’d love to hear from you.

The Role

We are seeking a motivated Research Associate to support our scientific team across in vivo and cell-based activities. This role is ideal for a recent graduate with some laboratory experience or an individual with 1–2 years of industry or academic research experience.

This is a great opportunity to gain broad exposure to early-stage biotech R&D, including programs ranging from early conception to IND enabling stages.

Schedule & Work Environment

This is a full-time position (Monday through Friday), on-site (San Carlos, CA).

We have an amazing space at MBC Biolabs, San Carlos (www.mbcbiolabs.com), which features:

• State of the art scientific instruments
• Fully stocked kitchen, regular catered scientific talks/events, and team lunches twice a week
• Dynamic community of biotech scientists and innovators
• Happy hours and ping pong tournaments

Your Experience

Bachelor's degree in the sciences. This role is perfect for new graduates with some laboratory experience and/or those who have 1-2 years of experience in industry / academia.

We’ll provide training in all key areas, but experience in any of the following is a plus (please mention in a brief cover letter if applicable):

• In vivo work (IP/IV injections, blood draws)
• PCR
• Molecular cloning (e.g., Gibson or Golden Gate assembly)
• Bacterial or mammalian cell culture
• DNA purification
• Chromatographic purification of biomolecules
• High throughput assays / pipetting (96- or 384-well)
• mRNA synthesis and lipid nanoparticle formulations
• Preparing lab media/reagents
• Maintaining a clean and organized lab environment
• Maintaining records of batches of reagents used different experiments

Compensation & Benefits

• $70,000-85,000 per year (depending on experience level)
• Significant equity compensation
• Performance-based bonus
• Full Health, Dental, and Vision insurance

To Apply

If you’re passionate about making a difference through science—and ready to learn fast and contribute to something meaningful—we’d love to meet you. Please send your resume and a short cover letter outlining your interest and relevant experience.

Tips: Provide a summary of the role, what success in the position looks like, and how this role fits into the organization overall.